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Plusvital - Equichek SAA

Plusvital Equichek SAA - Inflammation detection made simple

Previously, measuring SAA levels required sending a blood sample to a lab to run a specialist test which both took time and incurred costs. EquiChek SAA provides immediate results which empower the vet and trainer when managing the health of their horses.

  • Save time by checking your horses SAA levels on the spot

  • Save money testing for inflammation in horses

  • Identify a course of treatment for your horse immediately

  • Easily monitor your horses response to treatment

Why Measure SAA Levels?

SAA (Serum Amyloid A) is an acute phase protein that is normally present at very low concentrations in the horse but during infection or systemic inflammation the concentration increases dramatically. Therefore, measuring the SAA concentration provides a useful diagnostic aid to equine veterinarians.

What is SAA?

SAA (Serum Amyloid A) is a major acute phase protein that is usually present at low levels in a healthy horse’s blood. However, when the horse’s immune system begins to respond to either trauma, infection or inflammation, the concentration of SAA rises rapidly. Measuring the concentration of SAA can be a highly useful diagnostic aid when assessing the health status of the horse. In many cases, there may be no other symptoms of the infection/inflammation, the problem is sub-clinical, and EquiChek SAA can give early warning of an impending problem. SAA levels begin to fall rapidly as an infection/inflammation begin to resolve itself. In this way, SAA can also be used as a tool to monitor a horse’s response to treatment. 

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Research

Belgrave, 2013 Assesment of SAA testing

“ Serum amyloid A (SAA) is a major equine acute phase protein, the plasma concentrations of which increase during the acute phase response to every process that leads to tissue damage (e.g. infections, trauma, surgery, and neoplasia). The plasma concentrations of SAA start to increase a few hours after injury and reach high peak values within a few days. Furthermore, due to the short half-life of the protein, plasma SAA concentrations start to decline shortly after synthesis has ceased. These characteristics make SAA well suited for ‘realtime’ monitoring of acute inflammation.”

From Belgrave 

“Conclusions and Clinical Relevance—Results indicated that assessment of SAA concentration can provide valuable information regarding the clinical state of horses and may be more useful for patient monitoring and as a prognostic indicator than are traditional markers of inflammation. (J Am Vet Med Assoc 2013;243:113–119)”

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SAA Tutorial article 2007

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Comparison of Two Diagnostic Tests Measuring Equine Serum Amyloid A Levels in Inflamed Septic and Inflamed but Nonseptic Synovial Structures

" Sensitivity/specificity of SF SAA point-of-care test are very good when clinical signs of synovitis are present for more than 6 hours. This test, as an adjunct to traditional clinical methods, can assist equine practitioners to rapidly diagnose synovial sepsis."

John David Stack, MVB, MSc, MRCVS;
Matthieu Cousty, DMV, DECVS; Emma Steele, DMV;
Ian Handel, BVSc, MSc, PhD, Stat, MRCVS; Antoine Lechartier, DMV; and
Florent David, DVM, MSc, DACVS, DECVS, ECVDI Assoc., DACVSMR*

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